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            • Primary Antibodies ›
            • GCDH Antibodies

            Invitrogen

            GCDH Polyclonal Antibody

            Advanced Verification
            2 Published Figures
            2 References
            View all (14) GCDH antibodies

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            Datasheet
            Protocols
            Questions & Answers
            Catalog # PA5-60294
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            Price (USD)
            540.00
            100 µL
             
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            Datasheet
            Protocols
            Questions & Answers

            Cite GCDH Polyclonal Antibody

            • Antibody Testing Data (8)
            • Published Figures (2)
            • Advanced Verification (1)
            Application
            GCDH Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 11

            GCDH Antibody (PA5-60294) in ICC/IF

            Immunofluorecent analysis of GCDH in human cell line U-2 OS using GCDH Polyclonal Antibody (Product # PA5-60294). Staining shows positivity in mitochondria.
            View Product

            GCDH Antibody in Immunocytochemistry (ICC/IF)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Immunohistochemistry (IHC)
            GCDH Antibody in Western Blot (WB)
            GCDH Antibody in Western Blot (WB)
            GCDH Antibody in Western Blot (WB)
            GCDH Antibody

            Product Details

            PA5-60294

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            0.04-0.4 µg/mL
            View 1 publication 1 publication

            Immunohistochemistry (Paraffin) (IHC (P))

            1:50-1:200
            -

            Immunocytochemistry (ICC/IF)

            0.25-2 µg/mL
            -

            Immunoprecipitation (IP)

            -
            View 1 publication 1 publication
            Product Specifications

            Species Reactivity

            Human

            Published species

            Mouse

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Recombinant protein corresponding to Human GCDH. Recombinant protein control fragment (Product #RP-99006).
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.1 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            PBS, pH 7.2, with 40% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_2641910

            Product Specific Information

            Immunogen sequence: SRPEFDWQDP LVLEEQLTTD EILIRDTFRT YCQERLMPRI LLANRNEVFH REIISEMGEL GVLGPTIKGY GCAGV

            Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.

            Target Information

            The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Related Products for

            Bioinformatics

            Protein Aliases: GCD; Glutaryl-CoA dehydrogenase, mitochondrial; glutaryl-Coenzyme A dehydrogenase

            View more View less

            Gene Aliases: ACAD5; GCD; GCDH

            View more View less

            UniProt ID: (Human) Q92947

            View more View less

            Entrez Gene ID: (Human) 2639

            View more View less

            Function(s)

            fatty-acyl-CoA binding glutaryl-CoA dehydrogenase activity electron carrier activity flavin adenine dinucleotide binding oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor dehydrogenase

            Process(es)

            lysine catabolic process tryptophan metabolic process fatty acid beta-oxidation using acyl-CoA dehydrogenase fatty-acyl-CoA biosynthetic process lipid homeostasis
            It has to be done as per old AB suggested Products section.
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