Product References
Insulin Diminishes Superoxide Increase in Cytosol and Mitochondria of Cultured Cortical Neurons Treated with Toxic Glutamate.
International journal of molecular sciences
Pinelis V,Krasilnikova I,Bakaeva Z,Surin A,Boyarkin D,Fisenko A,Krasilnikova O,Pomytkin I
OPA1-06100 was used in Cell Culture to show that MK 801, an inhibitor of NMDAR-gated Ca2+ influx, completely abrogated the glutamate effects in both the presence and absence of insulin.
Thu Oct 20 00:00:00 EDT 2022
Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability.
Cardiovascular research
Hollier PL,Chapouly C,Diop A,Guimbal S,Cornuault L,Gadeau AP,Renault MA
OPA1-06100 was used in Immunocytochemistry to demonstrate that ectopically administered N-terminal Sonic Hedgehog (N-Shh) and endogenous endothelial-derived Desert Hedgehog (Dhh) induce opposite effects in endothelial cells (ECs).
Mon Nov 01 00:00:00 EDT 2021
Lasting alterations induced in glial cell phenotypes by short exposure to alcohol during embryonic development in zebrafish.
Addiction biology
Chatterjee D,Mahabir S,Chatterjee D,Gerlai R
Published figure using GFAP polyclonal antibody (Product # OPA1-06100) in Western Blot
Fri Jan 01 00:00:00 EST 2021
Lasting alterations induced in glial cell phenotypes by short exposure to alcohol during embryonic development in zebrafish.
Addiction biology
Chatterjee D,Mahabir S,Chatterjee D,Gerlai R
Published figure using GFAP polyclonal antibody (Product # OPA1-06100) in Western Blot
Fri Jan 01 00:00:00 EST 2021
The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar.
Molecular neurodegeneration
Conedera FM,Pousa AMQ,Mercader N,Tschopp M,Enzmann V
OPA1-06100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to indicate a pivotal role for TGFβ/Notch interplay in tuning Müller cell stemness during injury response and provide novel insights into the remodelling mechanism during retinal degenerative diseases.
Thu Sep 30 00:00:00 EDT 2021
The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar.
Molecular neurodegeneration
Conedera FM,Pousa AMQ,Mercader N,Tschopp M,Enzmann V
OPA1-06100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to indicate a pivotal role for TGFβ/Notch interplay in tuning Müller cell stemness during injury response and provide novel insights into the remodelling mechanism during retinal degenerative diseases.
Thu Sep 30 00:00:00 EDT 2021
The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar.
Molecular neurodegeneration
Conedera FM,Pousa AMQ,Mercader N,Tschopp M,Enzmann V
OPA1-06100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to indicate a pivotal role for TGFβ/Notch interplay in tuning Müller cell stemness during injury response and provide novel insights into the remodelling mechanism during retinal degenerative diseases.
Thu Sep 30 00:00:00 EDT 2021
The TGFβ/Notch axis facilitates Müller cell-to-epithelial transition to ultimately form a chronic glial scar.
Molecular neurodegeneration
Conedera FM,Pousa AMQ,Mercader N,Tschopp M,Enzmann V
OPA1-06100 was used in Immunohistochemistry (Paraffin), Immunohistochemistry to indicate a pivotal role for TGFβ/Notch interplay in tuning Müller cell stemness during injury response and provide novel insights into the remodelling mechanism during retinal degenerative diseases.
Thu Sep 30 00:00:00 EDT 2021
Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes).
Arteriosclerosis, thrombosis, and vascular biology
Chapouly C,Hollier PL,Guimbal S,Cornuault L,Gadeau AP,Renault MA
OPA1-06100 was used in Immunocytochemistry to investigate whether hedgehog coreceptors Gas1 (growth arrest-specific 1) and Cdon (cell adhesion molecule-related/downregulated by oncogenes) may be used as therapeutic targets to modulate Dhh signaling in ECs.
Tue Dec 01 00:00:00 EST 2020
Retinal microglia signaling affects Müller cell behavior in the zebrafish following laser injury induction.
Glia
Conedera FM,Pousa AMQ,Mercader N,Tschopp M,Enzmann V
OPA1-06100 was used in Immunohistochemistry-immunofluorescence to illustraate that microglia and Müller cell signaling is pivotal to unlock the regenerative potential of Müller cells in order to repair the damaged retina.
Sat Jun 01 00:00:00 EDT 2019
Targeting Brain Disease in MPSII: Preclinical Evaluation of IDS-Loaded PLGA Nanoparticles.
International journal of molecular sciences
Rigon L,Salvalaio M,Pederzoli F,Legnini E,Duskey JT,D'Avanzo F,De Filippis C,Ruozi B,Marin O,Vandelli MA,Ottonelli I,Scarpa M,Tosi G,Tomanin R
OPA1-06100 was used in Immunohistochemistry to show a significant reduction of GAG deposits in liver and brain tissues, as well as a reduction of some neurological and inflammatory markers (i.e., LAMP2, CD68, GFAP), highlighting a general improvement of the brain pathology.
Wed Apr 24 00:00:00 EDT 2019
A novel fluorescent imaging technique for assessment of cerebral vasospasm after experimental subarachnoid hemorrhage.
Scientific reports
Aum DJ,Vellimana AK,Singh I,Milner E,Nelson JW,Han BH,Zipfel GJ
Published figure using GFAP polyclonal antibody (Product # OPA1-06100) in Immunofluorescence
Tue Aug 22 00:00:00 EDT 2017
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
The Journal of biological chemistry
Eitas TK,Chou WC,Wen H,Gris D,Robbins GR,Brickey J,Oyama Y,Ting JP
OPA1-06100 was used in western blot to study the mechanism by which NLRX1 protects against experimental autoimmune encephalomyelitis
Fri Feb 14 00:00:00 EST 2014
Miz1 is required to maintain autophagic flux.
Nature communications
Wolf E,Gebhardt A,Kawauchi D,Walz S,von Eyss B,Wagner N,Renninger C,Krohne G,Asan E,Roussel MF,Eilers M
Published figure using GFAP polyclonal antibody (Product # OPA1-06100) in Immunohistochemistry
Thu May 01 00:00:00 EDT 2014
Behavioral and neurochemical alterations in mice deficient in anaplastic lymphoma kinase suggest therapeutic potential for psychiatric indications.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Bilsland JG,Wheeldon A,Mead A,Znamenskiy P,Almond S,Waters KA,Thakur M,Beaumont V,Bonnert TP,Heavens R,Whiting P,McAllister G,Munoz-Sanjuan I
OPA1-06100 was used in immunocytochemistry to investigate the role of receptor tyrosine kinase in the hematopoietic and neural systems
Fri Feb 01 00:00:00 EST 2008