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            • Primary Antibodies ›
            • GLT-1 Antibodies

            Invitrogen

            GLT-1 Polyclonal Antibody

            Advanced Verification
            5 Published Figures
            7 References
            View all (29) GLT-1 antibodies

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            Datasheet
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            Catalog # PA5-17099
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            Datasheet
            Protocols
            Questions & Answers

            Cite GLT-1 Polyclonal Antibody

            • Antibody Testing Data (2)
            • Published Figures (5)
            • Advanced Verification (1)
            Application
            GLT-1 Antibody in Western Blot (WB)
            Group 53 Created with Sketch.

            FIGURE: 1 / 8

            GLT-1 Antibody (PA5-17099) in WB

            Western blot was performed using Anti-GLT-1 Polyclonal Antibody, (Product # PA5-17099) and band at ~55 kDa corresponding to GLT-1 was observed in Mouse and Rat Brain and Cerebellum but not in Kidney and Lung which are reported to be negative. Tissue extracts (30 µg lysate) of Mouse Brain (Lane 1), Mouse Cerebellum (Lane 2), Mouse Kidney (Lane 3), Mouse Lung (Lane 4), Rat Brain (Lane 5), Rat Cerebellum (Lane 6), Rat Kidney (Lane 7) and Rat Lung (Lane 8) were electrophoresed using Novex® NuPAGE® 4-12% % Bis-Tris gel (Product # NP0322BOX). Re... View More
            View Product

            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody in Western Blot (WB)
            GLT-1 Antibody

            Product Details

            PA5-17099

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:1,000
            View 5 publications 5 publications

            Immunocytochemistry (ICC/IF)

            -
            View 1 publication 1 publication

            Miscellaneous PubMed (Misc)

            -
            View 1 publication 1 publication
            Product Specifications

            Species Reactivity

            Human, Mouse, Rat

            Published species

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Synthetic peptide corresponding to human EAAT2

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            22 µg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

            Contains

            no preservative

            Storage conditions

            -20°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            RRID

            AB_10978571

            Product Specific Information

            It is not recommended to aliquot this antibody.

            Target Information

            Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            Related Products for

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            Bioinformatics

            Protein Aliases: EAAT2 variant mEAAT2/5UT5; Excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; GLT-1; GLT1a; GLT1b; GLT1c; GLUT-R; glutamate transporter 1c; Glutamate/aspartate transporter II; high affinity glucose transporter; OTTHUMP00000165209; OTTHUMP00000165210; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; Solute carrier family 1 member 2; solute carrier family 1, member 2

            View more View less

            Gene Aliases: 1700091C19Rik; 2900019G14Rik; AI159670; EAAT2; Glt; GLT-1; GLT1; HBGT; MGLT1; SLC1A2

            View more View less

            UniProt ID: (Human) P43004, (Mouse) P43006, (Rat) P31596

            View more View less

            Entrez Gene ID: (Human) 6506, (Mouse) 20511, (Rat) 29482

            View more View less

            Function(s)

            L-glutamate transmembrane transporter activity high-affinity glutamate transmembrane transporter activity protein binding amino acid transmembrane transporter activity glutamate:sodium symporter activity symporter activity sodium:dicarboxylate symporter activity primary active transporter

            Process(es)

            amino acid transmembrane transport ion transport chemical synaptic transmission visual behavior response to wounding multicellular organism aging glutamate secretion telencephalon development adult behavior cellular response to extracellular stimulus multicellular organism growth response to drug response to amino acid positive regulation of glucose import L-glutamate import D-aspartate import L-glutamate transmembrane transport transport dicarboxylic acid transport nervous system development response to light stimulus L-glutamate transport sodium ion transmembrane transport neurotransmitter transport
            It has to be done as per old AB suggested Products section.
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