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Product Details
26456-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GMAP-210 Fusion Protein Ag13867 (1-67 aa encoded by BC002656)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.37 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: AMSSWLGGL GSGLGQSLGQ VGGSLASLTG QISNFTKDML MEGTEEVEAE LPDSRTKEIE AIHAILRSE (1-67 aa encoded by BC002656)
Target Information
The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Clonal evolution-related gene on chromosome 14 protein; GMAP-210; Golgi-associated microtubule-binding protein 210; Golgi-microtubule-associated protein of 210 kDa; Thyroid receptor-interacting protein 11; TR-interacting protein 11; Trip230
Gene Aliases: ACG1A; CEV14; GMAP-210; GMAP210; TRIP-11; TRIP11; TRIP230
UniProt ID: (Human) Q15643
Entrez Gene ID: (Human) 9321
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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