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The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB40, other ZBTB proteins, such as ZBTB4 bind methylated DNA and repress transcription. Single nucleotide polymorphisms near ZBTB40 have been linked to differences in bone mineral density of the hip and lumbar spine, and had a significant association with low-trauma fractures suggesting that ZBTB40 may be involved in bone development and formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA-binding protein p79PIF; Glucocorticoid modulatory element-binding protein 2; GMEB-2; Parvovirus initiation factor p79; parvovirus initiation factor, p79; PIF p79
Gene Aliases: GMEB-2; GMEB2; KIAA1269; P79PIF; PIF79
UniProt ID: (Human) Q9UKD1
Entrez Gene ID: (Human) 26205
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