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FIGURE: 1 / 1
GNAQ Antibody (H00002776-B02P) in WB
Western Blot analysis of GNAQ expression in transfected 293T cell line (H00002776-T02) by GNAQ MaxPab polyclonal antibody.
Lane 1: GNAQ transfected lysate(39.49 KDa).
Lane 2: Non-transfected lysate.
Lane 1: GNAQ transfected lysate(39.49 KDa).
Lane 2: Non-transfected lysate.
Product Details
H00002776-B02P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GNAQ (NP_002063.2, 1 a.a. approximately 359 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MTLESIMACC LSEEAKEARR INDEIERQLR RDKRDARREL KLLLLGTGES GKSTFIKQMR IIHGSGYSDE DKRGFTKLVY QNIFTAMQAM IRAMDTLKIP YKYEHNKAHA QLVREVDVEK VSAFENPYVD AIKSLWNDPG IQECYDRRRE YQLSDSTKYY LNDLDRVADP AYLPTQQDVL RVRVPTTGII EYPFDLQSVI FRMVDVGGQR SERRKWIHCF ENVTSIMFLV ALSEYDQVLV ESDNENRMEE SKALFRTIIT YPWFQNSSVI LFLNKKDLLE EKIMYSHLVD YFPEYDGPQR DAQAAREFIL KMFVDLNPDS DKIIYSHFTC ATDTENIRFV FAAVKDTILQ LNLKEYNLV
Target Information
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: guanine nucleotide binding protein (G protein), q polypeptide; Guanine nucleotide-binding protein alpha-q; Guanine nucleotide-binding protein G(q) subunit alpha
Gene Aliases: CMC1; G-ALPHA-q; GAQ; GNAQ; SWS
UniProt ID: (Human) P50148
Entrez Gene ID: (Human) 2776
skeletal system development
action potential
negative regulation of protein kinase activity
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of phospholipase C activity
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
heart development
blood coagulation
phototransduction, visible light
entrainment of circadian clock
post-embryonic development
neuron remodeling
forebrain neuron development
platelet activation
regulation of catenin import into nucleus
maternal behavior
embryonic digit morphogenesis
positive regulation of GTPase activity
regulation of melanocyte differentiation
developmental pigmentation
protein stabilization
phospholipase C-activating dopamine receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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