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Product Details
68191-1-IG
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Pig,
Rabbit,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
2H5G6
Immunogen
Recombinant protein
Conjugate
Form
Liquid
Purification
Protein A
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FTAMQAMIRA MDTLKIPYKY EHNKAHAQLV REVDVEKVSA FENPYVDAIK SLWNDPGIQE CYDRRREYQL SDSTKYYLND LDRVADPAYL PTQQDVLRVR VPTTGIIEYP FDLQSVIFRM VD
Target Information
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G alpha q; guanine nucleotide binding protein (G protein), q polypeptide; guanine nucleotide binding protein alpha q subunit; guanine nucleotide binding protein, alpha q polypeptide; guanine nucleotide regulatory protein G alpha q; Guanine nucleotide-binding protein alpha-q; guanine nucleotide-binding protein G(q) alpha subunit; Guanine nucleotide-binding protein G(q) subunit alpha; heterotrimeric guanine nucleotide-binding protein alpha q subunit
Gene Aliases: 1110005L02Rik; 6230401I02Rik; AA408290; AW060788; CMC1; Dsk1; Dsk10; G-ALPHA-q; Galphaq; GAQ; GNAQ; Gq; GqI; SWS
UniProt ID: (Human) P50148, (Pig) Q2PKF4, (Rat) P82471, (Mouse) P21279
Entrez Gene ID: (Human) 2776, (Pig) 654405, (Rat) 81666, (Mouse) 14682
GTPase activity
signal transducer activity
GTPase activator activity
protein binding
GTP binding
G-protein beta/gamma-subunit complex binding
type 2A serotonin receptor binding
metal ion binding
G-protein coupled receptor binding
protein complex binding
nucleotide binding
guanyl nucleotide binding
heterotrimeric G-protein
skeletal system development
action potential
negative regulation of protein kinase activity
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of phospholipase C activity
G-protein coupled acetylcholine receptor signaling pathway
glutamate receptor signaling pathway
heart development
blood coagulation
phototransduction, visible light
entrainment of circadian clock
post-embryonic development
neuron remodeling
forebrain neuron development
platelet activation
regulation of catenin import into nucleus
maternal behavior
embryonic digit morphogenesis
positive regulation of GTPase activity
regulation of melanocyte differentiation
developmental pigmentation
protein stabilization
phospholipase C-activating dopamine receptor signaling pathway
regulation of canonical Wnt signaling pathway
G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
metabolic process
positive regulation of apoptotic process
negative regulation of apoptotic process
negative regulation of potassium ion transport
positive regulation of smooth muscle cell proliferation
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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