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Immunogen sequence: MSSGASASAL QRLVEQLKLE AGVERIKVSQ AAAELQQYCM QNACKDALLV GVPAGSNPFR EPRSCALL; Positive Samples: U-251MG, HL-60, Mouse spleen, Rat spleen; Cellular Location: Cell membrane, Cytoplasmic side, Lipid-anchor
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Interacts with beta-1 and beta-2, but not with beta-3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: guanine nucleotide binding protein (G protein), gamma 10; guanine nucleotide binding protein 10; guanine nucleotide binding protein gamma 10 subunit; Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
Gene Aliases: AV006524; GNG10; GNGT10
UniProt ID: (Human) P50151, (Mouse) Q9CXP8
Entrez Gene ID: (Human) 2790, (Mouse) 14700, (Rat) 114119
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