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Invitrogen
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Immunogen sequence: RRKQMNLAYV KAADCISEPV NREPPSREAQ LLTLQNTSEF DILVIGGGAT GSG
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 87%.
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycerol-3-phosphate dehydrogenase 2 (mitochondrial); Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; testicular tissue protein Li 76
Gene Aliases: GDH2; GPD2; GPDM; mGPDH
UniProt ID: (Human) P43304
Entrez Gene ID: (Human) 2820
Molecular Function:
dehydrogenase
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