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Invitrogen
GPR123 Polyclonal Antibody
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Application
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GPR123 Antibody (PA5-60114) in IHC (P)
Immunohistochemical analysis of GPR123 in human lymph node using GPR123 Polyclonal Antibody (Product # PA5-60114) shows no positivity in non-germinal center cells as expected.
Product Details
PA5-60114
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GPR123. Recombinant protein control fragment (Product #RP-99985).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2642161
Product Specific Information
Immunogen sequence: PCKMTNLQAA QGHASCLSPA TPCCAKMHCE PLTADEAHVH LQEEGAFGHD PHLHGCLQGR TKPPYFSRHP AEEPEYAYHI PSSLDGSPRS SRTDSPPSSL DG
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 68%.
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. G protein coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR123 (G protein-coupled receptor 123) is a 1,279 amino acid multi-pass membrane protein belonging to the G-protein coupled receptor 2 family and LN-TM7 subfamily. Existing as two alternatively spliced isoforms, GPR123 functions as an orphan receptor that is expressed in adult and fetal brain, and in adult spinal cord. The gene encoding GPR123 maps to human chromosome 10q26.3 and mouse chromosome 7 F4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adhesion G protein-coupled receptor A1; G protein-coupled receptor 123; G-protein coupled receptor 123; probable G-protein coupled receptor 123
Gene Aliases: ADGRA1; GPR123; KIAA1828
UniProt ID: (Human) Q86SQ6
Entrez Gene ID: (Human) 84435
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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