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产品信息
PA5-33685
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 19 amino acid peptide from 3rd cytoplasmic domain of human GPR27.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2551062
产品详细信息
Percent identity with other species by BLAST analysis: Human, Mouse, Rat, Elephant, Panda (100%); Opossum (89%).
For IHC(P), use proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.
靶标信息
G protein coupled receptors (GPCRs) are a large family of receptors that have a similar structure characterized by 7 transmembrane domains. Activation of GPCRs by extracellular stimuli such as neurotransmitters, hormones, or light induces an intracellular signaling cascade mediated by heterotrimeric GTP-binding proteins, or G proteins. The 375 amino acid GPCR GPR27 protein contains several features of the GPCR family, including 7 transmembrane domains, potential N linked glycosylation sites in the N terminal extracellular domain, and conserved cysteine residues, which may form a disulfide bridge, in the first and second extracellular loops.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Probable G-protein coupled receptor 27; Super conserved receptor expressed in brain 1
基因别名: GPR27; SREB1
UniProt ID: (Human) Q9NS67, (Rat) Q9JJH3, (Mouse) O54897
Entrez Gene ID: (Human) 2850, (Rat) 65275, (Mouse) 14761
