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GPSM2 Antibody (PA5-87981) in WB
Western blot analysis of GPSM2 in extracts of various cell lines. Samples were incubated with GPSM2 Polyclonal antibody (Product # PA5-87981) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Product Details
PA5-87981
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 380-490 of human GPSM2 (NP_0374283)
Conjugate
Form
Liquid
Concentration
1.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2804561
Product Specific Information
Immunogen sequence: STNNSIMSEN TEIDSSLNGV RPKLGRRHSM ENMELMKLTP EKVQNWNSEI LAKQKPLIAK PSAKLLFVNR LKGKKYKTNS STKVLQDASN SIDHRIPNSQ RKISADTIGD E; Positive Samples: B cells, HeLa, Mouse brain, Mouse liver, Mouse kidney; Cellular Location: Cytoplasm, cell cortex
Target Information
The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein signalling modulator 2 (AGS3-like, C. elegans); G-protein-signaling modulator 2; HGNC:29501; LGN protein; Mosaic protein LGN; Pins homolog; pins homolog (Drosophia)
Gene Aliases: 6230410J09Rik; CMCS; DFNB82; GPSM2; LGN; PINS
UniProt ID: (Human) P81274, (Mouse) Q8VDU0
Entrez Gene ID: (Human) 29899, (Mouse) 76123
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