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Application
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GRHL3 Antibody (PA5-66299) in ICC/IF
Immunofluorescent staining of GRHL3 in human cell line MCF7 shows localization to nucleoplasm. Samples were probed using a GRHL3 Polyclonal Antibody (Product # PA5-66299).
Product Details
PA5-66299
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human GRHL3. Recombinant protein control fragment (Product #RP-106979).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2664197
Product Specific Information
Immunogen sequence: VNGDDDSVAAL SFLYDYYMGP KEKRILSSST GGRNDQGKRY YHGMEYETDL TPLESPTHLM KFLTENVSGT PEYPDLLKKN NLMSL
Highest antigen sequence identity to the following orthologs - mouse 84%, rat 86%.
Target Information
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with leader-binding protein 32 (LBP-32) and brother of mammalian grainyhead (BOM), and may function as a transcription factor during development. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional transcript variants have been described, but their biological nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Grainyhead-like protein 3 homolog; Sister of mammalian grainyhead; sister-of-mammalian grainyhead; Transcription factor CP2-like 4; transcription factor hSOM1
Gene Aliases: GRHL3; SOM; TFCP2L4; VWS2
UniProt ID: (Human) Q8TE85
Entrez Gene ID: (Human) 57822
establishment of planar polarity
neural tube closure
transcription from RNA polymerase II promoter
pattern specification process
ectoderm development
central nervous system development
epidermis development
regulation of actin cytoskeleton organization
wound healing
positive regulation of GTPase activity
positive regulation of transcription from RNA polymerase II promoter
eyelid development in camera-type eye
establishment of skin barrier
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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