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Product Details
PA5-116594
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GSDMC (NP_1136031)
Conjugate
Form
Liquid
Concentration
7.2 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2901225
Product Specific Information
Positive Samples: HeLa
Immunogen sequence: MPSMLERISK NLVKEIGSKD LTPVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG
Target Information
The N-terminal moiety promotes pyroptosis. May be acting by homooligomerizing within the membrane and forming pores (PubMed:27281216). The physiological relevance of this observation is unknown (Probable). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: gasdermin C1; Gasdermin-C; Gasdermin-C1; melanoma-derived leucine zipper, extra-nuclear factor; Melanoma-derived leucine zipper-containing extranuclear factor; mMLZE
Gene Aliases: GSDMC; Gsdmc1; MLZE
UniProt ID: (Human) Q9BYG8, (Mouse) Q99NB5
Entrez Gene ID: (Human) 56169, (Mouse) 83492
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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