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Proteintech

GSTA1 Polyclonal Antibody

14 篇参考文献

查看其他14个GSTA1抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (15)

Application

GSTA1 Antibody in Immunocytochemistry (ICC/IF)

图: 1 / 15

GSTA1 Antibody (14475-1-AP) in ICC/IF

Immunofluorescent analysis of HepG2 cells, using GSTA1 antibody 14475-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IGG (red).

GSTA1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

GSTA1 Antibody in Immunoprecipitation (IP)

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产品信息

14475-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:4,000

查看13篇已发表文章 13篇已发表文章

免疫组化 (IHC)

查看1篇已发表文章 1篇已发表文章

免疫组化（石蜡） (IHC (P))

1:200-1:800

免疫细胞化学 (ICC/IF)

1:10-1:100

免疫沉淀 (IP)

0.5-4.0 µg

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

GSTA1 Fusion Protein Ag5849 (1-222 aa encoded by BC053578)

查看免疫原

偶联物

Unconjugated

形式

Liquid

浓度

0.3 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MAEKPKLHY FNARGRMEST RWLLAAAGVE FEEKFIKSAE DLDKLRNDGY LMFQQVPMVE IDGMKLVQTR AILNYIASKY NLYGKDIKER ALIDMYIEGI ADLGEMILLL PVCPPEEKDA KLALIKEKIK NRYFPAFEKV LKSHGQDYLV GNKLSRADIH LVELLYYVEE LDSSLISSFP LLKALKTRIS NLPTVKKFLQ PGSPRKPPMD EKSLEEARKI FRF (1-222 aa encoded by BC053578)

靶标信息

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions.

Nature communications

Fan S,Yan Y,Xia Y,Zhou Z,Luo L,Zhu M,Han Y,Yao D,Zhang L,Fang M,Peng L,Yu J,Liu Y,Gao X,Guan H,Li H,Wang C,Wu X,Zhu H,Cao Y,Huang C

Thu Jun 08 00:00:00 UTC 2023

Rice protein suppresses 4-hydroxy-2-nonenal-induced inflammation owing to methionine availability.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme

Wang Z,Liang M,Li H,Liu B,Yang L

Mon Aug 01 00:00:00 UTC 2022

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

International journal of molecular sciences

Dahlke E,Engmann T,Anan Y,Häsler R,Solinas G,Theilig F

Mon Sep 05 00:00:00 UTC 2022

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

International journal of molecular sciences

Dahlke E,Engmann T,Anan Y,Häsler R,Solinas G,Theilig F

Mon Sep 05 00:00:00 UTC 2022

Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells.

PloS one

Ito Y,Oshinden K,Kutsuzawa N,Kohno C,Isaki S,Yokoyama K,Sato T,Tanaka M,Asano K

Fri Jan 08 00:00:00 UTC 2021

Rice Protein Exerts Endogenous Antioxidant Capacity via Methionine Sulfoxide Reductase and the Nrf2 Antioxidant System Independent of Age.

Journal of medicinal food

Li H,Liang M,Wang Z,Zhang Y,Wu Q,Yang L

Mon Jun 01 00:00:00 UTC 2020

Rice protein stimulates endogenous antioxidant response attributed to methionine availability in growing rats.

Journal of food biochemistry

Wang Z,Cai L,Li H,Liang M,Zhang Y,Wu Q,Yang L

Fri May 01 00:00:00 UTC 2020

γ-Oryzanol Improves Cognitive Function and Modulates Hippocampal Proteome in Mice.

Nutrients

Rungratanawanich W,Cenini G,Mastinu A,Sylvester M,Wilkening A,Abate G,Bonini SA,Aria F,Marziano M,Maccarinelli G,Memo M,Voos W,Uberti D

Sun Mar 31 00:00:00 UTC 2019

l-Methionine activates Nrf2-ARE pathway to induce endogenous antioxidant activity for depressing ROS-derived oxidative stress in growing rats.

Journal of the science of food and agriculture

Wang Z,Liang M,Li H,Cai L,He H,Wu Q,Yang L

Thu Aug 15 00:00:00 UTC 2019

l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L

Tue May 01 00:00:00 UTC 2018

l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Liang M,Wang Z,Li H,Cai L,Pan J,He H,Wu Q,Tang Y,Ma J,Yang L

Tue May 01 00:00:00 UTC 2018

Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.

Cell death & disease

Wang C,Xu W,Zhang Y,Huang D,Huang K

Thu Jul 26 00:00:00 UTC 2018

Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity.

Cell death & disease

Wang C,Xu W,Zhang Y,Huang D,Huang K

Thu Jul 26 00:00:00 UTC 2018

Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

The journals of gerontology. Series A, Biological sciences and medical sciences

Rojanathammanee L,Rakoczy S,Brown-Borg HM

Wed Oct 01 00:00:00 UTC 2014

Growth hormone alters the glutathione S-transferase and mitochondrial thioredoxin systems in long-living Ames dwarf mice.

The journals of gerontology. Series A, Biological sciences and medical sciences

Rojanathammanee L,Rakoczy S,Brown-Borg HM

Wed Oct 01 00:00:00 UTC 2014

Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Age (Dordrecht, Netherlands)

Rojanathammanee L,Rakoczy S,Kopchick J,Brown-Borg HM

Tue Mar 31 00:00:00 UTC 2015

Effects of insulin-like growth factor 1 on glutathione S-transferases and thioredoxin in growth hormone receptor knockout mice.

Age (Dordrecht, Netherlands)

Rojanathammanee L,Rakoczy S,Kopchick J,Brown-Borg HM

Tue Mar 31 00:00:00 UTC 2015

Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.

Journal of toxicologic pathology

Shirai M,Arakawa S,Miida H,Matsuyama T,Kinoshita J,Makino T,Kai K,Teranishi M

Sat Jun 01 00:00:00 UTC 2013

Thioacetamide-induced Hepatocellular Necrosis Is Attenuated in Diet-induced Obese Mice.

Journal of toxicologic pathology

Shirai M,Arakawa S,Miida H,Matsuyama T,Kinoshita J,Makino T,Kai K,Teranishi M

Sat Jun 01 00:00:00 UTC 2013

生物信息学

蛋白别名: 13-hydroperoxyoctadecadienoate peroxidase; Androst-5-ene-3,17-dione isomerase; class alpha; glutathione S-alkyltransferase A1; glutathione S-aryltransferase A1; glutathione S-transferase 2; Glutathione S-transferase A1; glutathione S-transferase A3 subunit; glutathione S-transferase A5; Glutathione S-transferase alpha-3; glutathione S-transferase Ha subunit 1; Glutathione S-transferase Ya; Glutathione S-transferase Ya1; Glutathione S-transferase Yc-1; glutathione S-transferase Yc1 subunit; Glutathione-S-transferase alpha type (Ya); GST; GST 2-2; GST A3-3; GST AA; GST class-alpha member 1; GST HA subunit 1; GST Yc1; GST-epsilon; GSTA1-1; GTH1; RP11-392A23.1; S-(hydroxyalkyl)glutathione lyase A1; testicular tissue protein Li 80

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基因别名: GST-epsilon; GST2; Gst2-1; Gsta; GSTA1; GSTA1-1; Gsta3; Gsta5; Gstya; Gstyc1; GTH1; OTTMUSG00000031890; Yc1

UniProt ID: (Human) P08263, (Rat) P04904, (Mouse) P13745

Entrez Gene ID: (Human) 2938, (Rat) 24421, (Mouse) 14857