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Positive Samples: HepG2, Mouse liver, Mouse kidney; Cellular Location: Cytoplasm
Immunogen sequence: MGLELYLDLL SQPCRAVYIF AKKNDIPFEL RIVDLIKGQH LSDAFAQVNP LKKVPALKDG DFTLTESVAI LLYLTRKYKV PDYWYPQDLQ ARARVDEYLA WQHTTLRRSC LRALWHKVMF PVFLGEPVSP QTLAATLAEL DVTLQLLEDK FLQNKAFLTG PHISLADLVA ITELMHPVGA GCQVFEGRPK LATWRQRVEA AVGEDLFQEA HEVILKAKDF PPADPTIKQK LMPWVLAMIR
Glutathione S-transferase (GST) theta 1 (GSTT1) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: alpha, mu, pi, theta, and zeta. The theta class includes GSTT1 and GSTT2. The GSTT1 and GSTT2 share 55% amino acid sequence identity and both of them were claimed to have an important role in human carcinogenesis. The GSTT1 gene is located approximately 50kb away from the GSTT2 gene. The GSTT1 and GSTT2 genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Glutathione S-transferase 1 (theta); Glutathione S-transferase 5; Glutathione S-transferase theta-1; Glutathione transferase T1-1; GST 5-5; GST class-theta-1
Gene Aliases: AI255817; GSTT1; Gstt1-1; GSTYRS
UniProt ID: (Human) P30711, (Rat) Q01579, (Mouse) Q64471
Entrez Gene ID: (Human) 2952, (Rat) 25260, (Mouse) 14871
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