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Immunogen sequence: SFGTQIIGG REVIPHSRPY MASLQRNGSH LCGGVLVHPK WVLTAAHCLA QRMAQLRLVL GLHTLDSPGL TFHIKAAIQH PRYKPVPALE NDLALLQLDG KVKPSRTIRP LALPSKRQVV AAGTRCSMAG WGLTHQGGRL SRVLRELDLQ VLDTRMCNNS RFWNGSLSPS MVCLAADSKD QAPCKGDSGG PLVCGKGRVL AGVLSFSSRV CTDIFKPPVA TAVAPYVSWI RKVTGRSA (21-257 aa encoded by BC025701 )
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Granzyme M; granzyme M (lymphocyte met-ase 1); HU-Met-1; lymphoctye Met-ase 1; lymphocyte met-ase 1; Met-1 serine protease; Met-ase; Natural killer cell granular protease; RNK-Met-1
Gene Aliases: GZMM; LMET1; MET1; MMET-1
UniProt ID: (Human) P51124
Entrez Gene ID: (Human) 3004, (Mouse) 16904, (Rat) 29252
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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