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Immunogen sequence: MAFSGSQAP YLSPAVPFSG TIQGGLQDGL QITVNGTVLS SSGTRFAVNF QTGFSGNDIA FHFNPRFEDG GYVVCNTRQN GSWGPEERKT HMPFQKGMPF DLCFLVQSSD FKVMVNGILF VQYFHRVPFH RVDTISVNGS VQLSYISFQP PGVWPANPAP ITQTVIHTVQ SAPGQMFSTP AIPPMMYPHP AYPMPFITTI LGGLYPSKSI LLSGTVLPSA QRFHINLCSG NHIAFHLNPR FDENAVVRNT QIDNSWGSEE RSLPRKMPFV RGQSFSVWIL CEAHCLKVAV DGQHLFEYYH RLRNLPTINR LEVGGDIQLT HVQT (1-323 aa encoded by BC110340)
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H and RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency. Multiple alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Ecalectin; Gal-9; Gal9; Galectin-9; Galectin9; HOM HD 21; lectin, galactose binding, soluble 5; lectin, galactoside binding soluble 9; lectin, galactoside-binding, soluble, 9; Tumor antigen HOM-HD-21; urate transporter/channel protein
Gene Aliases: AA407335; AI194909; AI265545; gal-9; galectin-9; HUAT; LGALS35; Lgals5; LGALS9; LGALS9A
UniProt ID: (Human) O00182, (Mouse) O08573
Entrez Gene ID: (Human) 3965, (Mouse) 16859
Molecular Function:
extracellular matrix protein
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