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QED Bioscience
Glutathione Reductase Monoclonal Antibody (2A2-1B7)
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Product Details
13901-200UG
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2A2-1B7
Immunogen
Recombinant human glutathione reductase purified from E. coli expressing the human glutathione reductase gene (aa 44-522).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5-1.0 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis luminal protein 75; epididymis secretory sperm binding protein Li 122m; glutathione reductase; Glutathione reductase, mitochondrial; glutathione S-reductase; GR; GRase
Gene Aliases: GLUR; GRD1; GSR; HEL-75; HEL-S-122m
UniProt ID: (Human) P00390
Entrez Gene ID: (Human) 2936
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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