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FIGURE: 1 / 1
Positive Samples: HeLa, NIH/3T3
Immunogen sequence: LPGEL
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
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Protein Aliases: H2B histone family, member B; H2B-clustered histone 5; H2B/a; H2B/b; H2B/g; H2B/h; H2B/k; H2B/l; HIRA-interacting protein 2; histone 1, H2bd; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.a; Histone H2B.b; Histone H2B.g; Histone H2B.h; Histone H2B.k; Histone H2B.l
Gene Aliases: dJ221C16.6; H2B.1B; H2B/b; H2BC10; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BFA; H2BFB; H2BFG; H2BFH; H2BFK; H2BFL; HIRIP2; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI
UniProt ID: (Human) P58876
Entrez Gene ID: (Human) 3017
Molecular Function: histone
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