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FIGURE: 1 / 3
Positive Samples: HeLa, NIH/3T3, C6
Immunogen sequence: AARKS
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
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Protein Aliases: H3 histone family, member A; H3 histone family, member C; H3 histone family, member D; H3 histone family, member F; H3 histone family, member L; H3-clustered histone 13; H3-clustered histone 14; H3-clustered histone 15; H3-clustered histone 2; H3-clustered histone 3; H3-clustered histone 4; H3-clustered histone 6; H3-clustered histone 7; histone 1, H3a; histone 1, H3b; histone 1, H3c; histone 1, H3e; histone 1, H3i; Histone H3.1; Histone H3.2; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; histone1, H3c
Gene Aliases: H3-143; H3-53; H3-B; H3-F; H3.1; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.f; H3/A; H3/c; H3/d; H3/f; H3/l; H3a; H3b; H3C1; H3C10; H3C11; H3C12; H3c13; H3c14; H3c15; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3FA; H3FB; H3FC; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3g; H3h; H3i; HIST1H3A; HIST1H3B; Hist1h3c; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; Hist2h3b; Hist2h3c1; Hist2h3c2; Hist2h3ca1; Hist2h3ca2
UniProt ID: (Human) P68431, (Mouse) P68433, (Mouse) P84228
Entrez Gene ID: (Human) 8350, (Human) 8358, (Human) 8352, (Human) 8353, (Human) 8354, (Mouse) 360198, (Mouse) 319150, (Mouse) 319148
Molecular Function: histone
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