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Immunogen sequence: SKFTCACPD QFKGKFCEIG SDDCYVGDGY SYRGKMNRTV NQHACLYWNS HLLLQENYNM FMEDAETHGI GEHNFCRNPD ADEKPWCFIK VTNDKVKWEY CDVSACSAQD VAYPEESPTE PSTKLPGFDS CGKTEIAERK IKRIYGGFKS TAGKHPWQAS LQSSLPLTIS MPQGHFCGGA LIHPCWVLTA AHCTDIKTRH LKVVLGDQDL KKEEFHEQSF RVEKIFKYSH YNERDEIPHN DIALLKLKPV DGHCALESKY VKTVCLPDGS FPSGSECHIS GWGVTETGKG SRQLLDAKVK LIANTLCNSR QLYDHMIDDS MICAGNLQKP GQDTCQGDSG GPLTCEKDGT YYVYGIVSWG LECGKRPGVY TQVTKFLNWI KATIKSESGF (172-560 aa encoded by BC031412)
HABP2 is an extracellularserine protease that binds hyaluronic acid and is involved in celladhesion. The encoded protein is synthesized as a single chain, butthen undergoes an autoproteolytic event to form the functionalheterodimer. Further autoproteolysis leads to smaller, inactivepeptides. This protease is known to cleave urinary plasminogenactivator, coagulation factor VII, and the alpha and beta chains offibrinogen, but not prothrombin, plasminogen, or the gamma chain offibrinogen. Two transcript variants encoding different isoformshave been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Factor seven-activating protease; factor VII activating protein; Factor VII-activating protease; FSAP; Hepatocyte growth factor activator-like protein; Hyaluronan-binding protein 2; hyaluronic acid binding protein 2; plasma hyalurona; plasma hyaluronan binding protein; Plasma hyaluronan-binding protein
Gene Aliases: FSAP; HABP; HABP2; HGFAL; NMTC5; PHBP
UniProt ID: (Human) Q14520
Entrez Gene ID: (Human) 3026
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