Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MKGALGSPVA AAGAAMQESF GCVVANRFHQ LLDDESDPFD ILREAERRRQ QQLQRKRRDE AAAAAGAGPR GGRSPAGASG HRAGAGGRRE SQKERKSLPA PVAQRPDSPG GGLQAPGQKR TPRRGEQQGW NDSRGPEGML ERAERRSYRE YRPYETERQA DFTAEKFPDE KVPELEVEEE TQVQEMTLDE WKNLQEQTRP KPEFNIRKPE STVPSKAVVI HKSKYRDDMV KDDYEDDSHV FRKPANDITS QLEINFGNLP RPGRGARGGT RGGRGRIRRA ENYGPRAEVV MQDVAPNPDD PEDFPALS
RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation (PubMed:14699138, PubMed:16455055, PubMed:19523114, PubMed:21771594). Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation (PubMed:19523114). Binds (via C-terminus) to poly(U) RNA (PubMed:19523114). Involved in mRNA translation regulation, probably at the initiation step (PubMed:21771594). Seems to play a role in PML-nuclear bodies formation (PubMed:28695742). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: chromodomain helicase DNA binding protein 3 interacting protein; HABP4; Hyaluronan-binding protein 4; IHABP-4; intracellular antigen detected by monoclonal antibody Ki-1; Intracellular hyaluronan-binding protein 4; Ki-1/57 intracellular antigen
Gene Aliases: HABP4; IHABP-4; IHABP4; Ki-1/57; SERBP1L
UniProt ID: (Human) Q5JVS0
Entrez Gene ID: (Human) 22927
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