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HEXIM1 Antibody (PA5-78336) in WB
Western blot was performed using Anti-HEXIM1 Polyclonal Antibody (Product # PA5-78336) and 53, 35 kDa bands corresponding to HEXIM1 was observed in HeLa, A549, HEL 92.1.7, HepG2 and not in SH-SY5Y and Daudi which are reported negative for HEXIM1 expression. Modified whole cell extracts (1% SDS) (30 µg lysate) of HeLa (Lane 1), A549 (Lane 2), HEL 92.1.7 (Lane 3), Hep G2 (Lane 4), SH-SY5Y (Lane 5) and Daudi (Lane 6) were electrophoresed using Novex® NuPAGE® 4-12 % Bis-Tris gel (Product # NP0322BOX). Resolved proteins were then transferred on... View More
Product Details
PA5-78336
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human HEXIM1. The exact sequence is proprietary.
Conjugate
Unconjugated
Form
Liquid
Concentration
0.68 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 0.1M glycine, 10% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2735900
Product Specific Information
Positive Control: HeLa, HepG2
Predicted Reactivity: Rhesus Monkey (95%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a member of the RecQ DNA helicase family. DNA helicases are enzymes involved in various types of DNA repair, including mismatch repair, nucleotide excision repair and direct repair. Some members of this family are associated with genetic disorders with predisposition to malignancy and chromosomal instability. The biological function of this helicase has not yet been determined. Two alternatively spliced transcripts, which encode the same isoform but differ in their 5' and 3' UTRs, have been described.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cardiac lineage protein 1; Estrogen down-regulated gene 1 protein; FLJ13562; hexamethylene bis-acetamide inducible 1; Hexamethylene bis-acetamide-inducible protein 1; hexamethylene bisacetamide-inducible protein; hexamethylene-bis-acetamide-inducible transcript 1; hexamthylene bis-acetamide inducible 1; HGNC:24953; HMBA-inducible; menage a quatre 1; Menage a quatre protein 1; Protein HEXIM1
Gene Aliases: CLP1; EDG1; HEXIM1; HIS1; MAQ1
UniProt ID: (Human) O94992
Entrez Gene ID: (Human) 10614
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
heart development
negative regulation of cyclin-dependent protein serine/threonine kinase activity
negative regulation of transcription, DNA-templated
positive regulation of signal transduction by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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