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Abnova
HHATL Monoclonal Antibody (2B7)
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Product Details
H00057467-M07A
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2B7
Immunogen
HHATL (NP_065758.2, 157 a.a. approximately 206 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: LISWQSGFVT GTFDLQEVLF HGGSSFTVLR CTSFALESCA HPDRHYSLAD
Target Information
HHATL (Hedgehog Acyltransferase-Like) is a gene that codes for a protein involved in the regulation of Hedgehog signaling pathways. HHATL is located on chromosome 7q36.3. Structurally, the protein encoded by this gene is characterized by an acyltransferase domain, which plays a crucial role in the N-palmitoylation of the Sonic Hedgehog (Shh) protein, a process essential for its proper signaling activity and distribution. Functionally, HHATL has been implicated in various biological processes, including amelioration of endoplasmic reticulum stress through autophagy. The gene is expressed in several tissues, with notable high expression in the heart, suggesting a potential role in cardiac development and function. Dysfunction in HHATL could lead to anomalies in Hedgehog signaling, impacting various developmental and cellular processes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glycerol uptake/transporter homolog; GUP1 glycerol uptake/transporter homolog; Hedgehog acyltransferase-like protein; membrane bound O-acyltransferase domain containing 3; Protein-cysteine N-palmitoyltransferase HHAT-like protein
Gene Aliases: C3orf3; GUP1; HHATL; KIAA1173; MBOAT3; MSTP002; OACT3
UniProt ID: (Human) Q9HCP6
Entrez Gene ID: (Human) 57467
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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