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Search Thermo Fisher Scientific
Immunogen sequence: MSETVPAAS ASAGVAAMEK LPTKKRGRKP AGLISASRKV PNLSVSKLIT EALSVSQERV GMSLVALKKA LAAAGYDVEK NNSRIKLSLK SLVNKGILVQ TRGTGASGSF KLSKKVIPKS TRSKAKKSVS AKTKKLVLSR DSKSPKTAKT NKRAKKPRAT TPKTVRSGRK AKGAKGKQQQ KSPVKARASK SKLTQHHEVN VRKATSK (1-206 aa encoded by BC069517)
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
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Protein Aliases: H1 histone family, member T (testis-specific); histone 1, H1t; Histone H1t; Testicular H1 histone
Gene Aliases: dJ221C16.2; H1-6; H1.6; H1f6; H1FT; H1T; HIST1H1T
UniProt ID: (Human) P22492, (Mouse) Q07133
Entrez Gene ID: (Human) 3010, (Mouse) 107970
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