Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 5
Positive test controls include: HepG2, HL-60, THP-1, NCI-H460, Mouse liver.
Immunogen sequence: MDSIGSSGLR QGEETLSCSE EGLPGPSDSS ELVQECLQQF KVTRAQLQQI QASLLGSMEQ ALRGQASPAP AVRMLPTYVG STPHGTEQGD FVVLELGATG ASLRVLWVTL TGIEGHRVEP RSQEFVIPQE VMLGAGQQLF DFAAHCLSEF LDAQPVNKQG LQLGFSFSFP CHQTGLDRST LISWTKGFRC SGVEGQDVVQ LLRDAIRRQG AYNIDVVAVV NDTVGTMMGC EPGVRPCEVG LVVDTGTNAC YMEEARHVAV LDEDRGRVCV
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ATP:D-hexose 6-phosphotransferase; hexokinase 3 (white cell); hexokinase iii; Hexokinase type III; Hexokinase-3; Hexokinase-C; Hexokinase3; HK III
Gene Aliases: HK III; HK-III; HK3; HKIII; HXK3; RNU73859
UniProt ID: (Human) P52790, (Rat) P27926, (Mouse) Q3TRM8
Entrez Gene ID: (Human) 3101, (Rat) 25060, (Mouse) 212032
Molecular Function: kinase
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