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Invitrogen
HMGA2 Polyclonal Antibody
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Application
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HMGA2 Antibody (PA5-25276) in WB
Western blot was performed using Anti-HMGA2 Polyclonal Antibody (Product # PA5-25276) and a 18 kDa band corresponding to High mobility group protein HMGI-C was observed. Nuclear enriched extracts (30 µg lysate) of HCT 116 (Lane 1), SW480 (Lane 2), HT-29 (Lane 3), Hep G2 (Lane 4), ACHN (Lane 5), Caki-1 (Lane 6), A549 (Lane 7), A549 treated with 10 ng/mL TGF-B1 for 48 hrs (Lane 8) and NIH/3T3 (Lane 9) were electrophoresed using NuPAGE™ 12% Bis-Tris Protein Gel (Product # NP0342BOX). Resolved proteins were then transferred onto a Nitrocellulo... View More
Product Details
PA5-25276
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 64-92 amino acids from the C-terminal region of human HMGA2
Conjugate
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2542776
Product Specific Information
This antibody is predicted to react with mouse based on sequence homology.
Target Information
HMGA2, previously known as HMGI-C, belongs to the group of high mobility chromosomal proteins that have the AT-hook DNA-binding motif. It is highly and ubiquitously expressed during embryogenesis. Chromosomal rearrangements of the HMGA2 gene and overexpression are frequently associated with benign and malignant tumors, respectively. Human and mouse HMGA2 shares 95% amino acid sequence identity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: High mobility group AT-hook protein 2; High mobility group protein HMGI-C; high-mobility group (nonhistone chromosomal) protein isoform I-C; High-mobility group protein HMGI-C
Gene Aliases: BABL; HMGA2; HMGI-C; HMGIC; LIPO; STQTL9
UniProt ID: (Human) P52926
Entrez Gene ID: (Human) 8091
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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