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Antibodies raised against RHAMM have been reported to recognize proteins of 56, 66 and 70 kDa in the supernatant of murine 3T3 fibroblasts. Some of the isoforms detectable by anti-RHAMM antibodies, including the 52 kDa form and a 48-49 kDa form found in 10T1/2 cells, have been speculated to be underglycosylated precursor forms of the mature RHAMM protein.
The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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Protein Aliases: CD168; Hyaluronan mediated motility receptor; hyaluronan-mediated motility receptor; hyaluronan-mediated motility receptor (RHAMM); Intracellular hyaluronic acid-binding protein; Receptor for hyaluronan-mediated motility
Gene Aliases: AA386826; CD168; HMMR; IHABP; RHAMM
UniProt ID: (Human) O75330, (Mouse) Q00547
Entrez Gene ID: (Human) 3161, (Rat) 25460, (Mouse) 15366
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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