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            • Primary Antibodies ›
            • hnRNP A1 Antibodies

            Proteintech

            HNRNPA1 Monoclonal Antibody (1A5A4), CoraLite® Plus 488

            View all (13) hnRNP A1 antibodies
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            Cite HNRNPA1 Monoclonal Antibody (1A5A4), CoraLite® Plus 488

            • Antibody Testing Data (1)
            Application
            HNRNPA1 Antibody in Immunocytochemistry (ICC/IF)
            Group 53 Created with Sketch.

            FIGURE: 1 / 1

            HNRNPA1 Antibody (CL48867844100UL) in ICC/IF

            Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite 488 HNRNPA1 antibody (Product # CL48867844100UL), Clone: 1A5A4 ) at dilution of 1:200.
            View Product

            HNRNPA1 Antibody in Immunocytochemistry (ICC/IF)

            Product Details

            CL48867844100UL

            Applications
            Tested Dilution
            Publications

            Immunocytochemistry (ICC/IF)

            1:50-1:500
            -
            Product Specifications

            Species Reactivity

            Human, Mouse

            Host/Isotype

            Mouse / IgG2b

            Class

            Monoclonal

            Type

            Antibody

            Clone

            1A5A4

            Conjugate

            CoraLite® Plus 488
            • Unconjugated
            • CoraLite 594
            • Request custom conjugation

            Excitation/Emission Max

            493/522 nm

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Protein A

            Storage buffer

            PBS, pH 7.3, with 50% glycerol, 0.5% BSA

            Contains

            0.05% ProClin 300

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles, store in dark

            Shipping conditions

            Wet ice

            Target Information

            HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre mRNAs in the nucleus and appear to influence pre mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. hnRNP A1 has two repeats of quasi RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re imported.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: HDP-1; Helix-destabilizing protein; Heterogeneous nuclear ribonucleoprotein A1; heterogeneous nuclear ribonucleoprotein A1B protein; heterogeneous nuclear ribonucleoprotein B2 protein; heterogeneous nuclear ribonucleoprotein core protein A1; hnRNP A1; hnRNP A1-like 3; hnRNP core protein A1; hnRNP core protein A1-like 3; hnRNP I; HNRNP-I; HNRNPI; HNRPA1MGC102835; HNRPI; MGC102835; nuclear ribonucleoprotein particle A1 protein; pPTB; PTB; PTB-1; PTB-T; PTB2; PTB3; PTB4; putative heterogeneous nuclear ribonucleoprotein A1-like 3; RP11-78J21.1; single-strand DNA-binding protein UP1; Single-strand RNA-binding protein; Single-strand-binding protein; Topoisomerase-inhibitor suppressed

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            Gene Aliases: ALS19; ALS20; Fli-2; Hdp; HDP-1; hnRNP A1; hnRNP-A1; HNRNPA1; HNRPA1; HNRPA1L3; IBMPFD3; Tis; UP 1

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            UniProt ID: (Human) P09651, (Mouse) P49312

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            Entrez Gene ID: (Human) 3178, (Mouse) 15382

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            Function(s)

            nucleotide binding single-stranded DNA binding RNA binding single-stranded RNA binding protein binding poly(A) RNA binding telomeric repeat-containing RNA binding G-rich strand telomeric DNA binding nucleic acid binding

            Process(es)

            mRNA splicing, via spliceosome mRNA processing RNA export from nucleus fibroblast growth factor receptor signaling pathway gene expression viral process negative regulation of telomere maintenance via telomerase positive regulation of telomere maintenance via telomerase mRNA transport nuclear export nuclear import alternative mRNA splicing, via spliceosome transport RNA splicing
            It has to be done as per old AB suggested Products section.
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