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HPS3 Antibody (PA5-115380) in IHC (P)
Immunohistochemistry analysis of HPS3 in mouse liver tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115380) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115380
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human HPS3(Accession Q969F9), corresponding to amino acid residues S537-V587.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900016
Product Specific Information
Antibody detects endogenous levels of total HPS3.
Target Information
This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. Alternate splice variants exist, but their full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BLOC-2 complex member HPS3; cocoa; Cocoa protein; DKFZp686F0413; FLJ22704; Hermansky-Pudlak syndrome 3 protein; Hermansky-Pudlak syndrome 3 protein homolog
Gene Aliases: BLOC2S1; Coa; HPS3; SUTAL
UniProt ID: (Human) Q969F9, (Mouse) Q91VB4
Entrez Gene ID: (Human) 84343, (Mouse) 12807, (Rat) 310288
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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