Proteintech

HPS5 Polyclonal Antibody

HPS5 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 11

HPS5 Antibody (13901-1-AP) in ICC/IF

Immunofluorescent analysis of MCF-7 cells, using HPS5 antibody 13901-1-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IGG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

HPS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Product Image Gallery

Product Details

13901-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 6 publications 6 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HPS5 Fusion Protein Ag4867 (661-1016 aa encoded by BC033640)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.43 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: CQFLKKYFF LLNLKRAKES IKLSYSNSPS VWDTFIEGLK EMASSNPVYM EMEKGDLPTR LKLLDDEVPF DSPLLVVYAT RLYEKFGESA LRSLIKFFPS ILPSDIIQLC HHHPAEFLAY LDSLVKSRPE DQRSSFLESL LQPESLRLDW LLLAVSLDAP PSTSTMDDEG YPRPHSHLLS WGYSQLILHL IKLPADFITK EKMTDICRSC GFWPGYLILC LELERRREAF TNIVYLNDMS LMKGDNGWIP ETVEEWKLLL HLIQSKSTRP APQESLNGSL SDGPSPINVE NVALLLAKAM GPDRAWSLLQ ECGLALELSE KFTRTCDILR IAEKRQRALI QSMLEKCDRF LWSQQA (661-1016 aa encoded by BC033640 )

Target Information

May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. Regulates intracellular vesicular trafficking in fibroblasts. May be involved in the regulation of general functions of integrins.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Oculocutaneous albinism and bleeding diathesis due to a novel deletion in the HPS3 gene.

Frontiers in genetics

Marek-Yagel D,Abudi-Sinreich S,Macarov M,Veber A,Shalva N,Philosoph AM,Pode-Shakked B,Malicdan MCV,Anikster Y

Wed Sep 07 00:00:00 EDT 2022

VWF maturation and release are controlled by 2 regulators of Weibel-Palade body biogenesis: exocyst and BLOC-2.

Blood

Sharda AV,Barr AM,Harrison JA,Wilkie AR,Fang C,Mendez LM,Ghiran IC,Italiano JE,Flaumenhaft R

Thu Dec 10 00:00:00 EST 2020

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.

PloS one

Stephen J,Yokoyama T,Tolman NJ,O'Brien KJ,Nicoli ER,Brooks BP,Huryn L,Titus SA,Adams DR,Chen D,Gahl WA,Gochuico BR,Malicdan MC

Thu Sep 07 00:00:00 EDT 2017

Cellular and molecular defects in a patient with Hermansky-Pudlak syndrome type 5.

PloS one

Stephen J,Yokoyama T,Tolman NJ,O'Brien KJ,Nicoli ER,Brooks BP,Huryn L,Titus SA,Adams DR,Chen D,Gahl WA,Gochuico BR,Malicdan MC

Thu Sep 07 00:00:00 EDT 2017

A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8.

Pigment cell & melanoma research

Cullinane AR,Curry JA,Golas G,Pan J,Carmona-Rivera C,Hess RA,White JG,Huizing M,Gahl WA

Sat Sep 01 00:00:00 EDT 2012

A BLOC-1 mutation screen reveals a novel BLOC1S3 mutation in Hermansky-Pudlak Syndrome type 8.

Pigment cell & melanoma research

Cullinane AR,Curry JA,Golas G,Pan J,Carmona-Rivera C,Hess RA,White JG,Huizing M,Gahl WA

Sat Sep 01 00:00:00 EDT 2012

A BLOC-1 mutation screen reveals that PLDN is mutated in Hermansky-Pudlak Syndrome type 9.

American journal of human genetics

Cullinane AR,Curry JA,Carmona-Rivera C,Summers CG,Ciccone C,Cardillo ND,Dorward H,Hess RA,White JG,Adams D,Huizing M,Gahl WA

Fri Jun 10 00:00:00 EDT 2011

A BLOC-1 mutation screen reveals that PLDN is mutated in Hermansky-Pudlak Syndrome type 9.

American journal of human genetics

Cullinane AR,Curry JA,Carmona-Rivera C,Summers CG,Ciccone C,Cardillo ND,Dorward H,Hess RA,White JG,Adams D,Huizing M,Gahl WA

Fri Jun 10 00:00:00 EDT 2011

Clinical, molecular, and cellular features of non-Puerto Rican Hermansky-Pudlak syndrome patients of Hispanic descent.

The Journal of investigative dermatology

Carmona-Rivera C,Golas G,Hess RA,Cardillo ND,Martin EH,O'Brien K,Tsilou E,Gochuico BR,White JG,Huizing M,Gahl WA

Thu Dec 01 00:00:00 EST 2011

Clinical, molecular, and cellular features of non-Puerto Rican Hermansky-Pudlak syndrome patients of Hispanic descent.

The Journal of investigative dermatology

Carmona-Rivera C,Golas G,Hess RA,Cardillo ND,Martin EH,O'Brien K,Tsilou E,Gochuico BR,White JG,Huizing M,Gahl WA

Thu Dec 01 00:00:00 EST 2011

Bioinformatics

Protein Aliases: alpha integrin binding protein 63; Alpha-integrin-binding protein 63; BLOC-2 complex member HPS5; Hermansky-Pudlak syndrome 5 protein; Hermansky-Pudlak syndrome 5 protein homolog; Ru2; ruby eye 2; Ruby-eye protein 2; Ruby-eye protein 2 homolog

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Gene Aliases: Aa2-028; Ab1-018; AI646796; AIBP63; AL022647; BLOC2S2; C85120; haze; HPS5; hz; KIAA1017; maroon; mr; ru-2; Ru2

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UniProt ID: (Human) Q9UPZ3, (Mouse) P59438

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Entrez Gene ID: (Human) 11234, (Mouse) 246694, (Rat) 308598

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Function(s)

protein binding

Process(es)

organelle organization blood coagulation pigmentation acute-phase response

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HPS5 Polyclonal Antibody

HPS5 Antibody (13901-1-AP) in ICC/IF

Product Details

13901-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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