Product References
HPV16 E6/E7 stabilize PGK1 protein by reducing its poly-ubiquitination in cervical cancer.
Cell biology international
Liu S,Song L,Yao H,Zhang L
28-0006 was used in Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot to show that PGK1 expression might serve as a prognostic biomarker in cervical cancer.
Tue Mar 01 00:00:00 EST 2022
Preclinical Development of Oncolytic Immunovirotherapy for Treatment of HPVPOS Cancers.
Molecular therapy oncolytics
Suksanpaisan L,Xu R,Tesfay MZ,Bomidi C,Hamm S,Vandergaast R,Jenks N,Steele MB,Ota-Setlik A,Akhtar H,Luckay A,Nowak R,Peng KW,Eldridge JH,Clarke DK,Russell SJ,Diaz RM
28-0006 was used in Western Blotting to study the use of vesicular stomatitis virus as a platform for the oncolytic immunovirotherapy of tumours expressing HPV target antigens.
Fri Sep 28 00:00:00 EDT 2018
GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
EMBO reports
Kayama K,Watanabe S,Takafuji T,Tsuji T,Hironaka K,Matsumoto M,Nakayama KI,Enari M,Kohno T,Shiraishi K,Kiyono T,Yoshida K,Sugimoto N,Fujita M
28-0006 was used in Western Blotting to show that glutamate-rich WD40 repeat containing 1 physically and functionally interacts with ribosomal protein L11.
Sun Jan 01 00:00:00 EST 2017
Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease.
International journal of cancer
Khan S,Oosterhuis K,Wunderlich K,Bunnik EM,Bhaggoe M,Boedhoe S,Karia S,Steenbergen RDM,Bosch L,Serroyen J,Janssen S,Schuitemaker H,Vellinga J,Scheper G,Zahn R,Custers J
28-0006 was used in Western Blot to study the development and pre-clinical testing of a vaccine candidate consisting of replication-deficient adenovirus type 26 and 35 based vectors for the interception of HPV16- and HPV18-related disease.
Sat Jul 15 00:00:00 EDT 2017
Development of a replication-deficient adenoviral vector-based vaccine candidate for the interception of HPV16- and HPV18-induced infections and disease.
International journal of cancer
Khan S,Oosterhuis K,Wunderlich K,Bunnik EM,Bhaggoe M,Boedhoe S,Karia S,Steenbergen RDM,Bosch L,Serroyen J,Janssen S,Schuitemaker H,Vellinga J,Scheper G,Zahn R,Custers J
28-0006 was used in Western Blot to study the development and pre-clinical testing of a vaccine candidate consisting of replication-deficient adenovirus type 26 and 35 based vectors for the interception of HPV16- and HPV18-related disease.
Sat Jul 15 00:00:00 EDT 2017
Spontaneous and Vaccine-Induced Clearance of Mus Musculus Papillomavirus 1 Infection.
Journal of virology
Jiang RT,Wang JW,Peng S,Huang TC,Wang C,Cannella F,Chang YN,Viscidi RP,Best SRA,Hung CF,Roden RBS
Published figure using HPV Type 16 E7 monoclonal antibody (Product # 28-0006) in Western Blot
Tue Aug 01 00:00:00 EDT 2017
Loss of Keratin 17 induces tissue-specific cytokine polarization and cellular differentiation in HPV16-driven cervical tumorigenesis in vivo.
Oncogene
Hobbs RP,Batazzi AS,Han MC,Coulombe PA
Published figure using HPV Type 16 E7 monoclonal antibody (Product # 28-0006) in Western Blot
Thu Oct 27 00:00:00 EDT 2016
The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC.
Journal of virology
Strickland SW,Vande Pol S
28-0006 was used in Western Blotting to study how human papillomavirus oncoproteins E6 and E7 manipulate cellular signalling cascades to promote the viral life cycle and cancer development.
Wed Jun 15 00:00:00 EDT 2016
Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes.
Nature genetics
Hobbs RP,DePianto DJ,Jacob JT,Han MC,Chung BM,Batazzi AS,Poll BG,Guo Y,Han J,Ong S,Zheng W,Taube JM,Čiháková D,Wan F,Coulombe PA
28-0006 was used in immunoprecipitation and western blot to report that autoimmune regulator is induced in human and mouse tumor keratinocytes in a K17-dependent manner and results in Gli2-induced skin tumorigenesis in mice
Sat Aug 01 00:00:00 EDT 2015
A functional interaction of E7 with B-Myb-MuvB complex promotes acute cooperative transcriptional activation of both S- and M-phase genes. (129 c).
Oncogene
Pang CL,Toh SY,He P,Teissier S,Ben Khalifa Y,Xue Y,Thierry F
28-0006 was used in western blot to study the interaction of human papillomaviruse E7 protein with B-Myb-MuvB complex and its effect on gene expression
Thu Jul 31 00:00:00 EDT 2014
Human papillomavirus 16 oncoprotein E7 stimulates UBF1-mediated rDNA gene transcription, inhibiting a p53-independent activity of p14ARF.
PloS one
Dichamp I,Séité P,Agius G,Barbarin A,Beby-Defaux A
28-0006 was used in immunoprecipitation to study the interaction between p14ARF and the human papillomavirus oncoprotein E7
Fri Jun 12 00:00:00 EDT 2015
Successful therapeutic vaccination with integrase defective lentiviral vector expressing nononcogenic human papillomavirus E7 protein.
International journal of cancer
Grasso F,Negri DR,Mochi S,Rossi A,Cesolini A,Giovannelli A,Chiantore MV,Leone P,Giorgi C,Cara A
Tue Jan 15 00:00:00 EST 2013
Successful therapeutic vaccination with integrase defective lentiviral vector expressing nononcogenic human papillomavirus E7 protein.
International journal of cancer
Grasso F,Negri DR,Mochi S,Rossi A,Cesolini A,Giovannelli A,Chiantore MV,Leone P,Giorgi C,Cara A
Tue Jan 15 00:00:00 EST 2013
Human papillomavirus E7 induces rereplication in response to DNA damage.
Journal of virology
Fan X,Liu Y,Heilman SA,Chen JJ
Published figure using HPV Type 16 E7 monoclonal antibody (Product # 28-0006) in Western Blot
Tue Jan 01 00:00:00 EST 2013
Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.
Journal of virology
Isaacson Wechsler E,Wang Q,Roberts I,Pagliarulo E,Jackson D,Untersperger C,Coleman N,Griffin H,Doorbar J
Fri Jun 01 00:00:00 EDT 2012
Reconstruction of human papillomavirus type 16-mediated early-stage neoplasia implicates E6/E7 deregulation and the loss of contact inhibition in neoplastic progression.
Journal of virology
Isaacson Wechsler E,Wang Q,Roberts I,Pagliarulo E,Jackson D,Untersperger C,Coleman N,Griffin H,Doorbar J
Fri Jun 01 00:00:00 EDT 2012
The E7 open reading frame acts in cis and in trans to mediate differentiation-dependent activities in the human papillomavirus type 16 life cycle.
Journal of virology
Bodily JM,Mehta KP,Cruz L,Meyers C,Laimins LA
Published figure using HPV Type 16 E7 monoclonal antibody (Product # 28-0006) in Western Blot
Thu Sep 01 00:00:00 EDT 2011
An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas.
American journal of cancer research
Zushi Y,Narisawa-Saito M,Noguchi K,Yoshimatsu Y,Yugawa T,Egawa N,Fujita M,Urade M,Kiyono T
28-0006 was used in Western Blot to indicate that either HRAS mutation or activation of EGFR in cooperation with MYC overexpression play critical roles in transformation of HTKs on a background of inactivation of the pRB and p53 pathways and telomerase activation.
Thu Nov 10 00:00:00 EST 2011
Localisation of human papillomavirus 16 E7 oncoprotein changes with cell confluence.
PloS one
Laurson J,Raj K
28-0006 was used in immunocytochemistry and western blot to investigate the localization of E7 from human papillomavirus type 16
Thu Dec 01 00:00:00 EST 2011
Differential sensitivity of the inner ear sensory cell populations to forced cell cycle re-entry and p53 induction.
Journal of neurochemistry
Sulg M,Kirjavainen A,Pajusola K,Bueler H,Ylikoski J,Laiho M,Pirvola U
28-0006 was used in immunocytochemistry to study the response of auditory and balance hair cells to forced cell cycle reactivation and p53 up-regulation.
Mon Mar 01 00:00:00 EST 2010
E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein.
Journal of virology
Handa K,Yugawa T,Narisawa-Saito M,Ohno S,Fujita M,Kiyono T
28-0006 was used in Western Blotting to suggest that DLG4 may function as a tumor suppressor in the development of HPV-associated cancers.
Thu Feb 01 00:00:00 EST 2007
Cervical keratinocytes containing stably replicating extrachromosomal HPV-16 are refractory to transformation by oncogenic H-Ras.
Virology
Berger KL,Barriga F,Lace MJ,Turek LP,Zamba GJ,Domann FE,Lee JH,Klingelhutz AJ
Published figure using HPV Type 16 E7 monoclonal antibody (Product # 28-0006) in Western Blot
Fri Jan 12 00:00:00 EST 2007
Two distinct activities contribute to human papillomavirus 16 E6's oncogenic potential.
Cancer research
Simonson SJ,Difilippantonio MJ,Lambert PF
Thu Sep 15 00:00:00 EDT 2005
Cyclin G1 has growth inhibitory activity linked to the ARF-Mdm2-p53 and pRb tumor suppressor pathways.
Molecular cancer research : MCR
Zhao L,Samuels T,Winckler S,Korgaonkar C,Tompkins V,Horne MC,Quelle DE
Wed Jan 01 00:00:00 EST 2003
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.
Cell
Debnath J,Mills KR,Collins NL,Reginato MJ,Muthuswamy SK,Brugge JS
Fri Oct 04 00:00:00 EDT 2002
The HPV E7 oncoprotein inhibits tumor necrosis factor alpha-mediated apoptosis in normal human fibroblasts.
Oncogene
Thompson DA,Zacny V,Belinsky GS,Classon M,Jones DL,Schlegel R,Münger K
Thu Jun 21 00:00:00 EDT 2001
The HPV E7 oncoprotein inhibits tumor necrosis factor alpha-mediated apoptosis in normal human fibroblasts.
Oncogene
Thompson DA,Zacny V,Belinsky GS,Classon M,Jones DL,Schlegel R,Münger K
Thu Jun 21 00:00:00 EDT 2001
Degradation of the retinoblastoma tumor suppressor by the human papillomavirus type 16 E7 oncoprotein is important for functional inactivation and is separable from proteasomal degradation of E7.
Journal of virology
Gonzalez SL,Stremlau M,He X,Basile JR,Münger K
28-0006 was used in Western Blot to demonstrate that pRB degradation is a direct activity of E7 and does not reflect a property of cell lines acquired during the selection process for E7 expression.
Wed Aug 01 00:00:00 EDT 2001
Preservation of the myofibroblastic phenotype of human papilloma virus 16 E6/E7 immortalized human bone marrow cells using the lineage limited alpha-smooth muscle actin promoter.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
Loeuillet C,Douay L,Hervé P,Chalmers DE
Tue May 01 00:00:00 EDT 2001
