Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
This antibody is specific to human HSF4.
Immunogen sequence: DRSPESLLP PMLLQPPQES VEPAGPLDVL GPSLQGREWT LMDLDMELSL MQPLVPERGE PELAVKGLNS PSPGKDPTLG APLLLDVQAA LGGPALGLPG ALTIYSTPES RTASYLGPEA SPSP (369-492 aa encoded by B C153061)
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AT-HSFB1; ATHSF4; binds heat shock DNA elements; cataract; DNA binding protein; heat shock factor 4; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner
Gene Aliases: CTM; CTRCT5; HSF 4; HSF4; HSTF 4; HSTF4; ldis1; mHSF4
UniProt ID: (Human) Q9ULV5, (Mouse) Q9R0L1
Entrez Gene ID: (Human) 3299, (Rat) 291960, (Mouse) 26386
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