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Product Details
MA5-17090
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
2E7
Immunogen
Purified recombinant fragment of human HSF4 expressed in E. Coli.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538561
Product Specific Information
MA5-17090 targets HSF4 in FACS, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17090 immunogen is purified recombinant fragment of human HSF4 expressed in E. Coli.
MA5-17090 detects HSF4 which has a predicted molecular weight of approximately 53kDa.
Target Information
Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AT-HSFB1; ATHSF4; cataract; Heat shock factor protein 4; Heat shock transcription factor 4; hHSF4; HSF 4; HSFB1; HSTF 4; Marner
Gene Aliases: CTM; CTRCT5; HSF4
UniProt ID: (Human) Q9ULV5
Entrez Gene ID: (Human) 3299
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
visual perception
positive regulation of cell proliferation
histone H3-K9 demethylation
camera-type eye development
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
cell development
protein homotrimerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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