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Immunogen sequence: LAFILSRATP RPALGPLSYR EHRVALLHLT HSMSTTGRGV TFTINCSGF
Highest antigen sequence identity to the following orthologs: Mouse - 33%, Rat - 27%.
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. HTR3E encodes a subunit E of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. Genes encoding subunits C, D and E form a cluster on chromosome 3. An alternative splice variant has been described but its full length sequence has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5-HT3-E; 5-hydroxytryptamine (serotonin) receptor 3, family member E; 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic; 5-hydroxytryptamine receptor 3 subunit E; 5-hydroxytryptamine receptor 3E; Serotonin receptor 3E
Gene Aliases: 5-HT3-E; 5-HT3c1; 5-HT3E; HTR3E
UniProt ID: (Human) A5X5Y0
Entrez Gene ID: (Human) 285242
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