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            • Primary Antibodies ›
            • HSP60 Antibodies

            OriGene

            Hsp60 (HSPD1) Monoclonal Antibody (OTI3A2), TrueMAB™

            View all (94) HSP60 antibodies
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            Catalog # TA800758
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            Price (USD)
            540.00
             
            Estimated availability date: 05-Jun-2025
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            Cite Hsp60 (HSPD1) Monoclonal Antibody (OTI3A2), TrueMAB™

            • Antibody Testing Data (15)
            Application
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 15

            Hsp60 (HSPD1) Antibody (TA800758) in IHC (P)

            Immunohistochemical staining of paraffin-embedded human pancreas tissue within the normal limits using anti-Hsp60 (HSPD1) mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min, TA800758)
            View Product

            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Hsp60 (HSPD1) Antibody in Western Blot (WB)
            Hsp60 (HSPD1) Antibody in Western Blot (WB)

            Product Details

            TA800758

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:150
            -
            Product Specifications

            Species Reactivity

            Dog, Human, Mouse

            Host/Isotype

            Mouse / IgG2a

            Class

            Monoclonal

            Type

            Antibody

            Clone

            OTI3A2

            Immunogen

            Full length human recombinant protein of human HSPD1 produced in E.coli.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            1 mg/mL

            Purification

            Affinity chromatography

            Storage buffer

            PBS with 1% BSA, 50% glycerol

            Contains

            0.02% sodium azide

            Storage conditions

            -20°C, Avoid Freeze/Thaw Cycles

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Target Information

            This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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            Cite this product

            Bioinformatics

            Protein Aliases: 60 kDa chaperonin; 60 kDa heat shock protein; 60 kDa heat shock protein, mitochondrial; Chaperonin 60; CPN60; heat shock 60kDa protein 1 (chaperonin); Heat shock protein; Heat shock protein 60; heat shock protein 65; Heat shock protein family D member 1; heat shock protein, 60 kDa; HSP; HSP-60; HSP-65; Hsp60s1; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; short heat shock protein 60 Hsp60s1

            View more View less

            Gene Aliases: 60kDa; CPN60; GROEL; HLD4; HSP-60; HSP60; HSP65; HSPD1; HuCHA60; SPG13

            View more View less

            UniProt ID: (Human) P10809, (Mouse) P63038

            View more View less

            Entrez Gene ID: (Dog) 478854, (Human) 3329, (Mouse) 15510

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            Function(s)

            ATP binding isomerase activity lipopolysaccharide binding p53 binding DNA replication origin binding single-stranded DNA binding double-stranded RNA binding protein binding ATPase activity ubiquitin protein ligase binding poly(A) RNA binding unfolded protein binding chaperone binding nucleotide binding protease binding protein complex binding insulin binding protein heterodimerization activity misfolded protein binding

            Process(es)

            detection of misfolded protein B cell cytokine production MyD88-dependent toll-like receptor signaling pathway positive regulation of T cell mediated immune response to tumor cell protein folding activation of cysteine-type endopeptidase activity involved in apoptotic process response to unfolded protein positive regulation of interferon-alpha production positive regulation of interferon-gamma production positive regulation of interleukin-10 production positive regulation of interleukin-12 production positive regulation of interleukin-6 production protein refolding B cell proliferation T cell activation B cell activation positive regulation of macrophage activation positive regulation of apoptotic process negative regulation of apoptotic process negative regulation of neuron apoptotic process isotype switching to IgG isotypes positive regulation of inflammatory response protein stabilization positive regulation of T cell activation chaperone mediated protein folding requiring cofactor 'de novo' protein folding response to cold viral process chaperone-mediated protein complex assembly protein maturation
            It has to be done as per old AB suggested Products section.
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