Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MGSLFPLSLL FFLAAAYPGV GSALGRRTKR AQSPKGSPLA PSGTSVPFWV RMSPEFVAVQ PGKSVQLNCS NSCPQPQNSS LRTPLRQGKT LRGPGWVSYQ LLDVRAWSSL AHCLVTCAGK TRWATSRITA YSVPGGLLGG DPEAWKPGHL FRKPGALHRP GSGQRDLDLR VCCWTPRLLA ARDLPRAPQS RRPGGPQQLG THYTDARLEP RAHSFGLRFH RCPCRDPPHC GRCVPMQVPS YEVPGVKGDV LCRLSEKKRN MKQSGEMAIH GG
This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CD242; CD242 antigen; ICAM-4; Intercellular adhesion molecule 4; intercellular adhesion molecule 4 (LW blood group); intercellular adhesion molecule 4 isoform 3 anitgen LWa; Landsteiner-Wiener blood group antigen a; Landsteiner-Wiener blood group glycoprotein; LW blood group protein
Gene Aliases: CD242; ICAM4; LW
UniProt ID: (Human) Q14773
Entrez Gene ID: (Human) 3386
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