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Purity is > 95% by SDS-PAGE.
This gene (IFNGR2) encodes the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X-linked inheritance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: AF-1; IFN-gamma receptor 2; IFN-gamma-R-beta; IFN-gamma-R2; Interferon gamma receptor 2; Interferon gamma receptor accessory factor 1; interferon gamma receptor accessory factor-1; interferon gamma receptor beta chain; Interferon gamma receptor beta-chain; Interferon gamma transducer 1
Gene Aliases: AF-1; IFGR2; Ifgt; IFNGR2; IFNGT1; IMD28
UniProt ID: (Human) P38484
Entrez Gene ID: (Human) 3460, (Rat) 360697, (Mouse) 15980
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