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Immunogen Sequence: GLTYEKLNRL DEALDCFLKL HAILRNSAEV LYQIANIYEL MENPSQAIEW LMQVVSVIPT DPQVLSKLGE LYDREGDKSQ AFQYYYESYR YFPCNIEVIE WLGAYYIDTQ FWEKAIQYFE RASLIQPTQV KWQLMVASCF RRSGNYQKAL DTYKDTHRKF PENVECLRFL VRLCTDLGLK DAQEYARKLK RLEKMKEIRE QRIKSGRDGS GGSRGKREGS ASGDSGQNYS ASSKGERLSA RLRALPGTNE PYESSSNKEI DASYVDPLGP QIERPKTAAK KRIDEDDFAD EELGDDLLPE
This gene encodes a member of the tetratrico peptide repeat family. Mutations of a similar gene in mouse can cause polycystic kidney disease. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Protein Aliases: HGNC:20606; intraflagellar transport 88 homolog; Intraflagellar transport protein 88 homolog; MGC26259; polaris homolog; probe hTg737 (polycystic kidney disease, autosomal recessive); Recessive polycystic kidney disease protein Tg737; Recessive polycystic kidney disease protein Tg737 homolog; RP11-172H24.2; testicular tissue protein Li 93; tetratricopeptide repeat domain 10; Tetratricopeptide repeat protein 10; Tg737 protein; TgN(Imorpk)737Rpw; TPR repeat protein 10; transgene insert site 737, insertional mutation, polycystic kidney disease
Gene Aliases: AW552028; D13S1056E; DAF19; flexo; fxo; hTg737; IFT88; orpk; polaris; TG737; Tg737Rpw; TgN737Rpw; TTC10
UniProt ID: (Human) Q13099, (Mouse) Q61371
Entrez Gene ID: (Human) 8100, (Mouse) 21821, (Rat) 305918
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