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Application
FIGURE: 1 / 1
IKAP Antibody (PA5-111320) in IHC (P)
Immunohistochemical analysis of IKAP in human pancreas using IKAP Polyclonal Antibody (Product # PA5-111320) shows moderate cytoplasmic and nuclear positivity in exocrine glandular cells.
Product Details
PA5-111320
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein corresonding to Human IKAP. Recombinant protein control fragment (Product #RP-103837).
Conjugate
Unconjugated
Form
Liquid
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2856730
Product Specific Information
Immunogen sequence: RLHVLCQGWH YLAYDWHWTT DRSVGDNSSD LSNVAVIDGN RVLVTVFRQT VVPPPMCTYQ LLFPHPVNQV TFLAHPQKSN DLAVLDASNQ ISVYKCGDCP SADPTVKLGA VG
Target Information
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781H1425; elongator acetyltransferase complex subunit 1; Elongator complex protein 1; ELP1; FLJ12497; IkappaB kinase complex-associated protein; IKK complex-associated protein; p150; RP11-3J11.4
Gene Aliases: DYS; ELP1; FD; IKAP; IKBKAP; IKI3; TOT1
UniProt ID: (Human) O95163
Entrez Gene ID: (Human) 8518
tRNA wobble uridine modification
regulation of transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
protein complex assembly
protein phosphorylation
immune response
signal transduction
positive regulation of cell migration
regulation of protein kinase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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