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Invitrogen
IKBIP Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-65219
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human IKBIP. Recombinant protein control fragment (Product #RP-104692).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2663800
Product Specific Information
Immunogen sequence: DSTLRNIRTVK RQEEEDLLRV EEQLGSDTKA IEKLEEEQHA LFARDEDLTN KLSDYEPKVE ECKTHLPTIE SAI
Highest antigen sequence identity to the following orthologs - mouse 85%, rat 84%.
Target Information
IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: I kappa B kinase interacting protein; I kappa-B kinase-interacting protein; IKBKB-interacting protein; IKK interacting protein; IKK-interacting protein; Inhibitor of nuclear factor kappa-B kinase-interacting protein
Gene Aliases: IKBIP; IKIP
UniProt ID: (Human) Q70UQ0
Entrez Gene ID: (Human) 121457
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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