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Proteintech

INTS5 Polyclonal Antibody

5 References

View all (9) INTS5 antibodies

Datasheet

Protocols

Questions & Answers

Datasheet

Protocols

Questions & Answers

Antibody Testing Data (10)

Application

INTS5 Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

INTS5 Antibody (14069-1-AP) in ICC/IF

Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using 14069-1-AP (INTS5 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

INTS5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

INTS5 Antibody in Immunoprecipitation (IP)

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Product Details

14069-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2400

View 5 publications 5 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:20-1:200

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

INTS5 Fusion Protein Ag5129 (1-322 aa encoded by BC060841)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

0.29 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSALCDPPG APGPPGPAPA THGPAPLSAQ ELSQEIKAFL TGVDPILGHQ LSAREHARCG LLLLRSLPPA RAAVLDHLRG VFDESVRAHL AALDETPVAG PPHLRPPPPS HVPAGGPGLE DVVQEVQQVL SEFIRANPKA WAPVISAWSI DLMGQLSSTY SGQHQRVPHA TGALNELLQL WMGCRATRTL MDIYVQCLSA LIGSCPDACV DALLDTSVQH SPHFDWVVAH IGSSFPGTII SRVLSCGLKD FCVHGGAGGG AGSSGGSSSQ TPSTDPFPGS PAIPAEKRVP KIASVVGILG HLASRHGDSI RRELLRMFHD SLA (1-322 aa encoded by BC060841)

Target Information

INTS5 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

A combinatorial approach to uncover an additional Integrator subunit.

Cell reports

Offley SR,Pfleiderer MM,Zucco A,Fraudeau A,Welsh SA,Razew M,Galej WP,Gardini A

Tue Mar 28 00:00:00 UTC 2023

INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II.

Molecular cell

Hu S,Peng L,Song A,Ji YX,Cheng J,Wang M,Chen FX

Thu May 18 00:00:00 UTC 2023

INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.

Nature communications

Mascibroda LG,Shboul M,Elrod ND,Colleaux L,Hamamy H,Huang KL,Peart N,Singh MK,Lee H,Merriman B,Jodoin JN,Sitaram P,Lee LA,Fathalla R,Al-Rawashdeh B,Ababneh O,El-Khateeb M,Escande-Beillard N,Nelson SF,Wu Y,Tong L,Kenney LJ,Roy S,Russell WK,Amiel J,Reversade B,Wagner EJ

Thu Oct 13 00:00:00 UTC 2022

RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.

Cell reports

Wang X,Qi Y,Wang Z,Wang L,Song A,Tao B,Li J,Zhao D,Zhang H,Jin Q,Jiang YZ,Chen FX,Xu Y,Chen X

Tue Apr 26 00:00:00 UTC 2022

Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.

Science (New York, N.Y.)

Zheng H,Qi Y,Hu S,Cao X,Xu C,Yin Z,Chen X,Li Y,Liu W,Li J,Wang J,Wei G,Liang K,Chen FX,Xu Y

Fri Nov 27 00:00:00 UTC 2020

Bioinformatics

Protein Aliases: Int5; Integrator complex subunit 5

Gene Aliases: 1110055N21Rik; INT5; INTS5; KIAA1698; mKIAA1698; RGD1309370

UniProt ID: (Human) Q6P9B9, (Mouse) Q8CHT3

Entrez Gene ID: (Human) 80789, (Rat) 309200, (Mouse) 109077

Function(s)

Process(es)

Performance Guarantee

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