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IQCC Antibody (PA5-55944) in ICC/IF
Immunofluorecent analysis of IQCC in human cell line A-431 using IQCC Polyclonal Antibody (Product # PA5-55944). Staining shows localization to vesicles.
产品信息
PA5-55944
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2642759
产品详细信息
Immunogen sequence: CVRGFLVRRQ FQSLRAEYEA IVREVEGDLG TLQWTEGRIP RPRFLPEKAK SHQTWKAGDR VANPEQGLWN HFPCEESEGE ATWEEMVLKK S
Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 65%.
靶标信息
The IQCC (IQ Motif Containing C) gene encodes a protein that contains the IQ motif, which is known for its role in binding calmodulin and other proteins with EF-hand calcium-binding motifs. IQCC is located on chromosome 6 at position 6q16.1. The IQCC protein is involved in several cellular processes, including signaling pathways related to intracellular calcium levels and regulation of ion channels. Additionally, recent studies have indicated its potential involvement in cancer biology, where disruptions in its expression or function may contribute to tumorigenesis. The exact molecular mechanisms and pathways influenced by IQCC are still under investigation, and elucidating these aspects could uncover new therapeutic targets for various diseases, including cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: IQ domain-containing protein C; RP4-622L5.6
基因别名: IQCC
UniProt ID: (Human) Q4KMZ1
Entrez Gene ID: (Human) 55721
