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IVD Antibody (PA5-90345) in IHC (P)
Immunohistochemistry analysis of IVD in paraffin-embedded human colon carcinoma. Samples were incubated with IVD Polyclonal antibody (Product # PA5-90345) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-90345
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 33-200 of human IVD (NP_0022162)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806036
Product Specific Information
Immunogen sequence: HSLLPVDDAI NGLSEEQRQL RQTMAKFLQE HLAPKAQEID RSNEFKNLRE FWKQLGNLGV LGITAPVQYG GSGLGYLEHV LVMEEISRAS GAVGLSYGAH SNLCINQLVR NGNEAQKEKY LPKLISGEYI GALAMSEPNA GSDVVSMKLK AEKKGNHYIL NGNKFWIT; Positive Samples: MCF7, Mouse heart, Mouse kidney, Mouse liver; Cellular Location: Mitochondrion matrix
Target Information
Isovaleryl-CoA dehydrogenase (IVD) is a mitochondrial matrix enzyme that catalyzes the third step in leucine catabolism. The genetic deficiency of IVD results in an accumulation of isovaleric acid, which is toxic to the central nervous system and leads to isovaleric acidemia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Butyryl-CoA dehydrogenase; isovaleryl CoA dehydrogenase; isovaleryl Coenzyme A dehydrogenase; isovaleryl dehydrogenase; Isovaleryl-CoA dehydrogenase, mitochondrial; IVD
Gene Aliases: 1300016K07Rik; 6720455E18Rik; ACAD2; AI463340; IVD
UniProt ID: (Human) P26440, (Rat) P12007, (Mouse) Q9JHI5
Entrez Gene ID: (Human) 3712, (Rat) 24513, (Mouse) 56357
fatty-acyl-CoA binding
isovaleryl-CoA dehydrogenase activity
electron carrier activity
flavin adenine dinucleotide binding
oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor
acyl-CoA dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the CH-CH group of donors
dehydrogenase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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