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            Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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            • Primary Antibodies ›
            • KDM2A Antibodies

            Bethyl Laboratories

            JHDM1A Polyclonal Antibody

            View all (14) KDM2A antibodies
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            Cite JHDM1A Polyclonal Antibody

            • Antibody Testing Data (3)
            Application
            JHDM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            Group 53 Created with Sketch.

            FIGURE: 1 / 3

            JHDM1A Antibody (A301-475A) in IHC (P)

            Detection of human JHDM1A by immunohistochemistry. Sample: FFPE section of human breast cancer. Antibody: Affinity purified rabbit anti-JHDM1A (Product # A301-475A) (Lot 3) used at a dilution of 1:200 (1 µg/mL). Detection: DAB.
            View Product

            JHDM1A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
            JHDM1A Antibody in Western Blot (WB)
            JHDM1A Antibody in Immunoprecipitation (IP)

            Product Details

            A301-475A

            Applications
            Tested Dilution
            Publications

            Western Blot (WB)

            1:2,000-1:10,000
            -

            Immunohistochemistry (IHC)

            1:100-1:500
            -

            Immunohistochemistry (Paraffin) (IHC (P))

            1:100-1:500
            -

            Immunoprecipitation (IP)

            2-10 µg/mg lysate
            -
            Product Specifications

            Species Reactivity

            Human

            Host/Isotype

            Rabbit / IgG

            Class

            Polyclonal

            Type

            Antibody

            Immunogen

            Region between residue 825 and 875 of human JmjC domain-containing histone demethylation protein 1A.
            View immunogen

            Conjugate

            Unconjugated

            Form

            Liquid

            Concentration

            0.20 mg/mL

            Purification

            Antigen affinity chromatography

            Storage buffer

            TBS, pH 7.0 to 8.0, with 0.1% BSA

            Contains

            0.09% sodium azide

            Storage conditions

            4°C

            Shipping conditions

            Ambient (domestic); Wet ice (international)

            Product Specific Information

            The recommended shelf life for this product is 1 year from date of receipt.

            Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

            Target Information

            FBXL11 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box). The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXL11 belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats.

            For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

            References (0)

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            Cite this product

            Bioinformatics

            Protein Aliases: [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; DKFZp434M1735; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FLJ00115; FLJ46431; JmjC domain-containing histone demethylation protein 1A; jumonji C domain-containing histone demethylase 1A; lysine (K)-specific demethylase 2A; Lysine-specific demethylase 2A; SF-KDM2A

            View more View less

            Gene Aliases: CXXC8; FBL11; FBL7; FBXL11; JHDM1A; KDM2A; KIAA1004; LILINA

            View more View less

            UniProt ID: (Human) Q9Y2K7

            View more View less

            Entrez Gene ID: (Human) 22992

            View more View less

            Function(s)

            DNA binding zinc ion binding histone demethylase activity histone demethylase activity (H3-K36 specific)

            Process(es)

            double-strand break repair via nonhomologous end joining transcription, DNA-templated regulation of transcription, DNA-templated oxidation-reduction process histone H3-K36 demethylation
            It has to be done as per old AB suggested Products section.
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            Performance Guarantee

            If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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