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Invitrogen
JMJD1B Monoclonal Antibody (S.393.0)
Application
FIGURE: 1 / 10
JMJD1B Antibody (MA5-14792) in ICC/IF
Knockdown of JMJD1B was achieved by transfecting IMR-32 cells with JMJD1B specific siRNA (Silencer® select Product # s28657, s224243). Immunofluorescence analysis was performed on untransfected IMR-32 cells (panel a,d), transfected with non-specific scrambled siRNA (panels b,e) and transfected with JMJD1B specific siRNA (panel c,f). Cells were fixed, permeabilized, and labelled with JMJD1B Monoclonal Antibody (S.393.0) (Product # MA5-14792, 1:200 dilution) followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, A... View More
Product Details
MA5-14792
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Monoclonal
Type
Antibody
Clone
S.393.0
Immunogen
Synthetic peptide corresponding to the sequence of the human JMJD1B protein
Conjugate
Unconjugated
Form
Liquid
Concentration
49 µg/mL
Purification
Affinity chromatography
Storage buffer
0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol
Contains
<0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_10979162
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: [histone H3]-dimethyl-L-lysine(9) demethylase 3B; JmjC domain-containing histone demethylation protein 2B; jumonji domain containing 1B; Jumonji domain-containing protein 1B; lysine (K)-specific demethylase 3B; Lysine-specific demethylase 3B; Nuclear protein 5qNCA
Gene Aliases: 5qNCA; C5orf7; JHDM2B; JMJD1B; KDM3B; KIAA1082; NET22
UniProt ID: (Human) Q7LBC6
Entrez Gene ID: (Human) 51780
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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