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Protein glucosyltransferase that catalyzes the transfer of glucose from UDP-glucose to a serine residue within the consensus sequence peptide C-X-N-T-X-G-S-F-X-C. Can also catalyze the transfer of xylose from UDP-xylose but less efficiently. Specifically targets extracellular EGF repeats of proteins such as NOTCH1 and NOTCH3. May regulate the transport of NOTCH1 and NOTCH3 to the plasma membrane and thereby the Notch signaling pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Endoplasmic reticulum resident protein 58; ER protein 58; KDEL (Lys-Asp-Glu-Leu) containing 1; KDEL motif-containing 1; KDEL motif-containing protein 1; Protein O-glucosyltransferase 2; Protein O-xylosyltransferase POGLUT2
Gene Aliases: EP58; ERp58; KDEL1; KDELC1; POGLUT2; UNQ1910/PRO4357
UniProt ID: (Human) Q6UW63
Entrez Gene ID: (Human) 79070
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