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Proteintech
KIF5B Recombinant Rabbit Monoclonal Antibody (2B18), CoraLite® Plus 488
产品信息
CL488-82485
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2B18
抗原
KIF5B fusion protein Ag16250
偶联物
CoraLite® Plus 488
激发/发射光谱
493/522 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: ESVDALSEEL VQLRAQEKVH EMEKEHLNKV QTANEVKQAV EQQIQSHRET HQKQISSLRD EVEAKAKLIT DLQDQNQKMM LEQERLRVEH EKLKATDQEK SRKLHELTVM QDRREQARQD L
靶标信息
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner. Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes. Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Conventional kinesin heavy chain; epididymis secretory protein Li 61; kif5b {ECO:0000312|EMBL:ABC25059.1}; kinesin 1 (110-120kD); kinesin heavy chain; kinesin heavy chain member 5B, ubiquitous; Kinesin-1 heavy chain; U-KHC; Ubiquitous kinesin heavy chain; UKHC
基因别名: AL022807; HEL-S-61; Khc; Khcs; KIF5B; KINH; KNS; KNS1; UKHC
UniProt ID: (Human) P33176, (Mouse) Q61768, (Rat) Q2PQA9
Entrez Gene ID: (Human) 3799, (Mouse) 16573, (Rat) 117550
