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Product Details
BS-22217R-BIOTIN
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human KRG2/DDX11
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX11 encodes a DEAD box protein, which is an enzyme that possesses both ATPase and DNA helicase activities. DDX11 is a homolog of the yeast CHL1 gene, and may function to maintain chromosome transmission fidelity and genomestability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent DNA helicase DDX11; CHL1-like helicase homolog; CHL1-related helicase gene-1; CHL1-related protein 1; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (CHL1-like helicase homolog, S. cerevisiae); DEAD/H box protein 11; DEAD/H-box protein 11; DNA 5'-3' helicase DDX11; hCHLR1; Keratinocyte growth factor-regulated gene 2 protein; KRG-2; probable ATP-dependent RNA helicase DDX11
Gene Aliases: 4732462I11Rik; CHL1; CHLR1; DDX11; essa15a; KRG2; WABS
UniProt ID: (Human) Q96FC9, (Mouse) Q6AXC6
Entrez Gene ID: (Human) 1663, (Mouse) 320209, (Rat) 316767
double-stranded DNA binding
single-stranded DNA binding
RNA binding
ATP-dependent DNA helicase activity
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleotide binding
nucleic acid binding
DNA binding
ATP-dependent helicase activity
hydrolase activity
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
iron-sulfur cluster binding
DNA helicase
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